Son of the dramatist Luigi Pirandello, he trained with the sculptor Lipinsky between 1919 and 1920, before turning to painting.
After a few years in Paris, Pirandello returned to Rome in 1931 and was welcomed into the Roman School, distinguishing himself by his originality and solitary research. His approach was oriented towards a realism of daily life. 
In the 1950s, Pirandello developed his style further, reabsorbing cubist suggestions from Braque and Picasso. He offered new solutions between abstraction and figuration, with paintings that refer strongly towards a cubist synthesis in the tiling of colors. This was particularly the case in his series of «female « Nudos » in the 1950s which this painting is a striking example. 
Pirandello exhibited widely. This painting on cardboard was presented at the Rome Quadriennale in 1954 and at the Kanagawa museum of modern art in Japan in 1955. 

This painting is referenced in the catalogo generale published by Ferrari in 1990, number 547.